In Alien Resurrection (2000, exclusive to PS1), some of the doors will refuse to open if you play on an emulator or PS3 console... but not if you play on real hardware.
Ex-member of Argonaut Games has released old versions of Alien Resurrection | NeoGAF
Alien: Resurrection (Video Game 2000) - IMDb
Alien: Resurrection (PS1) - Player Expendable" by civvie11 from Patreon | Kemono
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Alien Resurrection (PS1) Playthrough longplay video game - YouTube
Alien: Resurrection (Video Game 2000) - IMDb
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Alien Resurrection - game-rave.com - Alien Games on PlayStation
Alien: Resurrection Screenshots For PlayStation MobyGames | xn--90absbknhbvge.xn--p1ai:443